Methods for improved hemorrhage control

نویسنده

  • John B Holcomb
چکیده

Trauma is the leading cause of death from age 1 to 34 years and is the fifth leading cause of death overall in the USA, with uncontrolled hemorrhage being the leading cause of potentially preventable death. Improving our ability to control hemorrhage may represent the next major hurdle in reducing trauma mortality. New techniques, devices, and drugs for hemorrhage control are being developed and applied across the continuum of trauma care: prehospital, emergency room, and operative and postoperative critical care. This brief review focuses on drugs directed at life-threatening hemorrhage. The most important of these new drugs are injectable hemostatics, fibrin foams, and dressings. The available animal studies are encouraging and human studies are required.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New methods of hemorrhage Control in Pre-Hospital and Battlefield Conditions: Mini Review

Background and Aim: Hemorrhage has been a major cause of casualties on the battlefield, which can be prevented in many cases. The aim of this study was to evaluate the results of hemorrhage control methods in pre-hospital and battlefield conditions. Methods: In this mini-review, search was conducted using different combination of keywords including Hemorrhage control, Hemorrhage blocking agents...

متن کامل

Survey the effect of bed-rest and sandbag on hematoma and hemorrhage after ‎coronary angiography

Introduction: Cardiovascular disease is one of the leading major causes of death in the world. ‎Coronary angiography is the most important routine diagnostic procedure for coronary artery ‎disease.‎ Objective: The aim of this study is to assess the effect of bed-rest duration time and sandbag ‎time on hematoma and hemorrhage after coronary angiography.‎ Methods: This stud...

متن کامل

Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery

Introduction: Endoscopic sinus surgery is a common procedure performed by otolaryngologists. This study evaluated the efficacy of intravenous (IV) tranexamic acid (TA) on hemorrhage  in patients undergoing elective endoscopic sinus surgery (ESS).   Materials and Methods: The present study was performed in 170 patients scheduled for ESS surgery under general anesthesia in order to examine the ef...

متن کامل

Effect of Bakri Balloon on Managing Postpartum Hemorrhage: A Case Series

Postpartum hemorrhage (PPH) is among the most significant causes of maternal death worldwide. The time of diagnosing and the proper management of hemorrhage are essential in preventing maternal mortality. The current study aimed to evaluate the effect of Bakri balloon on the management of PPH. Bakri balloon was effective in controlling PPH of 92.3% of patients. The most frequent indications for...

متن کامل

P84: Effect of Insulin-Like Growth Factor 2 (IGF2) as a Microglia-Derived Anti-Iinflammatory Ccytokine on Improving Memory Impairment Following Hippocampal Intracerebral Hemorrhage in Rat

Insulin-like growth factor 2 (IGF2) as a microglia-derived anti-inflammatory cytokine has a pivotal activity in memory consolidation. However, there is limited evidence on brain cell-originated IGF2 expression, regulation and function in pathological condition and neuro-inflammation. Hence, the present study was conducted to investigate the effect of IGF2 on improving the memory impairment in a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2004